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Selected Publications

Vigil, F.A., Bozdemir, E., Veraza, R.J., Bugay, V., Holstein, D.M., Hobbs, M, Sanchez, I, Brenner, R, Lechleiter, J.D. and M.S. Shapiro.  (2020).  Augmentation of KCNQ (Kv7, “M-type”) K+ currents as a post-event treatment for traumatic brain injury. J. Cerebral Blood Flow & Metabolism 40(6):1256-1273.

 

Vigil FA, Carver CM, Shapiro MS. Pharmacological manipulation of Kv7 channels as a new therapeutic tool for multiple brain disorders. (2020). Frontiers in Physiology 11(19):688. 

Archer, C.R., Enslow, B., Bhattacharya, A., Taylor, A. and M.S. Shapiro.  (2019).  A mutually-induced conformational fit underlies Ca2+-directed interactions between calmodulin and the proximal carboxy terminus of KCNQ4 K+ channels. 294:6094-6112. 

Carver, C.M. and M.S. Shapiro (2019).  Gq-coupled muscarinic receptor enhancement of KCNQ2/3 channels and activation of TRPC channels in multimodal control of excitability in dentate gyrus granule cells. J. Neuroscience. 39:1566-1587. 

Choveau, F., Bierbower, S.M, Reed, P., Hernandez, C., C., and M. S. Shapiro (2018). Phosphatidylinositol 4,5-bisphosphate (PIP2) regulates KCNQ3 K+ channels through multiple sites of action.  Journal of Biological Chemistry 293(50):19411-19428. 

Vigil FA, Mizuno K, Lucchesi W, Valls-Comamala V, Giese KP. (2017) Prevention of long-term memory loss after retrieval by an endogenous CaMKII inhibitor. Science Reports 7(1):4040.

Zhang, J., Carver, C.C., Choveau F., and M.S. Shapiro.  (2016). Clustering and functional coupling of diverse ion channels and signaling proteins revealed by super-resolution STORM microscopy in neurons.  Neuron.  Oct 19;92(2):461-478.

Zhang, J. and M. S. Shapiro (2012).  Activity-dependent transcriptional regulation of M-type K+ channels by AKAP79/150-mediated NFAT actions. Neuron 76:1133-46. 

Choveau, F.S., Hernandez, C.C., Bierbower, S.M. and M. S. Shapiro (2012).  Pore determinants of KCNQ3 K+ current expression. Biophysical Journal 102:2489-2498. 

Zhang, J., Bal, M, Zaika, O., and M. S. Shapiro (2011). AKAP79/150 signal complexes in G-protein modulation of neuronal ion channels.  Journal of Neuroscience 31:7199-7211. 

Zaika, O., Zhang J. and M. S. Shapiro (2011). Combined phosphoinositide and calcium signals mediating receptor specificity toward neuronal Ca2+ channels. Journal of Biological Chemistry 286:830-41. 

Bal, M., Zhang J., Hernandez C.C., Zaika O., and M.S. Shapiro (2010). Ca2+/calmodulin disrupts AKAP79/150 interactions with KCNQ (M-type) K+ channels. Journal of Neuroscience 30:2311-23.

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